Whether to admire more the man or his method, the life or the work, I leave for the readers of this well-told story to decide. Among the researches that have made the name of Pasteur a household word in the civilised world, three are of the first importance—a knowledge of the true nature of the processes in fermentation—a knowledge of the chief maladies which have scourged3 man and animals—a knowledge of the measures by which either the body may be protected against these diseases, or the poison neutralised when once within the body.
I.
Our knowledge of disease has advanced in a curiously5 uniform way. The objective features, the symptoms, naturally first attracted attention. The Greek physicians, Hippocrates, Galen, and Aretaeus, gave excellent accounts of many diseases; for example, the forms of malaria6. They knew, too, very well, their modes of termination, and the art of prognosis was studied carefully. But of the actual causes of disease they knew little or nothing, and any glimmerings of truth were obscured in a cloud of theory. The treatment was haphazard9, partly the outcome of experience, partly based upon false theories of the cause of the disease. This may be said to have been the sort of knowledge possessed10 by the profession until{vi} men began to study the “seats and causes” of disease, and to search out the changes inside the body, corresponding to the outward symptoms and the external appearances. Morbid11 anatomy12 began to be studied, and in the hundred years from 1750 to 1850 such colossal13 strides were made that we knew well the post-mortem appearances of the more common diseases; the recognition of which was greatly helped by a study of the relation of the pathological appearances with the signs and symptoms. The 19th century may be said to have given us an extraordinarily14 full knowledge of the changes which disease produces in the solids and fluids of the body. Great advances, too, were made in the treatment of disease. We learned to trust Nature more and drugs less; we got rid (in part) of treatment by theory, and we ceased to have a drug for every symptom. But much treatment was, and still is, irrational15, not based on a knowledge of the cause of the disease. In a blundering way many important advances were made, and even specifics were discovered—cinchona, for example, had cured malaria for a hundred and fifty years before Laveran found the cause. At the middle of the last century we did not know much more of the actual causes of the great scourges16 of the race, the plagues, the fevers and the pestilences17, than did the Greeks. Here comes in Pasteur’s great work. Before him Egyptian darkness; with his advent18 a light that brightens more and more as the years give us ever fuller knowledge. The facts that fevers were catching19, that epidemics20 spread, that infection could remain attached to particles of clothing, etc., all gave support to the view that the actual cause was something alive, a contagium vivum. It was really a very old view, the germs of which may be found in the Fathers, but which was first clearly expressed—so far as I know—by Frascastorius, a Veronese physician in the 16th century, who spoke22 of the seeds of contagion23 passing from one person to another; and he first drew a parallel between the processes of contagion and the fermentation of wine. This was more than one hundred years before Kircher, Leeuwenhoek, and others, began to use the microscope and to see{vii} animalcul?, etc., in water, and so gave a basis for the “infinitely little” view of the nature of disease germs. And it was a study of the processes of fermentation that led Pasteur to the sure ground on which we now stand. Starting as a pure chemist, and becoming interested in the science of crystallography, it was not until his life at Lille, a town with important brewing24 industries, that Pasteur became interested in the biological side of chemical problems. Many years before it had been noted25 by Cagniard-Latour that yeast26 was composed of cells capable of reproducing themselves by a sort of budding, and he made the keen suggestion that it was possibly through some effect of their vegetation that the sugar was transformed. But Liebig’s view everywhere prevailed that the ferment2 was an alterable, organic substance which exercised a catalytic force, transforming the sugar. It was in August, 1857, that Pasteur sent his famous paper on Lactic27 Acid Fermentation to the Lille Scientific Society; and in December of the same year he presented to the Academy of Sciences a paper on Alcoholic28 Fermentation, in which he concluded that the deduplication of sugar into alcohol and carbonic acid is correlevant to a phenomena29 of life. These studies had the signal effect of diverting the man from the course of his previous more strictly30 chemical studies. It is interesting to note how slowly these views dislocated the dominant31 theories of Liebig. More than ten years after their announcement I remember that we had in our chemical lectures the catalytic theory very fully7 presented.
Out of these researches arose a famous battle which kept Pasteur hard at work for four or five years—the struggle over spontaneous generation. It was an old warfare32, but the microscope had revealed a new world, and the experiments on fermentation had lent great weight to the omne vivum ex ovo doctrine33. The famous Italians, Redi and Spallanzani, had led the way in their experiments, and the latter had reached the conclusion that there is no vegetable and no animal that has not its own germ. But heterogenesis became the burning question, and Pouchet in France, and Bastian in England,{viii} led the opposition34 to Pasteur. The many famous experiments carried conviction to the minds of scientific men, and destroyed for ever the old belief in spontaneous generation. All along the analogy between disease and fermentation must have been in Pasteur’s mind; and then came the suggestion: “What would be most desirable would be to push those studies far enough to prepare the road for a serious research into the origin of various diseases.” If the changes in lactic, alcohol and butyric fermentations are due to minute living organisms, why should not the same tiny creatures make the changes which occur in the body in the putrid35 and suppurative diseases. With an accurate training as a chemist, having been diverted in his studies upon fermentation into the realm of biology, and nourishing a strong conviction of the identity between putrefactive changes of the body and fermentation, Pasteur was well prepared to undertake investigations37, which had hitherto been confined to physicians alone.
The first outcome of the researches of Pasteur upon fermentation and spontaneous generation represents a transformation38 in the practice of surgery, which, it is not too much to say, has been one of the greatest boons39 ever conferred upon humanity. It had long been recognised that now and again a wound healed without the formation of pus, that is without suppuration, but both spontaneous and operative wounds were almost invariably associated with that change; and, moreover, they frequently became putrid, as it was then called—infected, as we should say; the general system became involved, and the patient died of blood poisoning. So common was this, particularly in old, ill-equipped hospitals, that many surgeons feared to operate, and the general mortality in all surgical40 cases was very high. Believing that from outside the germs came which caused the decomposition41 of wounds, just as from the atmosphere the sugar solution got the germs which caused the fermentation, a young surgeon at Glasgow, Joseph Lister, applied42 the principles of Pasteur’s experiments to their treatment. It may be well here to quote from Lister’s original paper in the Lancet, 1867:—“Turning now to the question{ix} how the atmosphere produces decomposition of organic substances, we find that a flood of light has been thrown upon this most important subject by the philosophic43 researches of M. Pasteur, who has demonstrated by thoroughly44 convincing evidence that it is not to its oxygen or to any of its gaseous45 constituents46 that the air owes this property, but to minute particles suspended in it, which are the germs of various low forms of life, long since revealed by the microscope, and regarded as merely accidental concomitants of putrescence, but now shown by Pasteur to be its essential cause, resolving the complex organic compounds into substances of simpler chemical constitution, just as the yeast plant converts sugar into alcohol and carbonic acid.” From these beginnings modern surgery took its rise, and the whole subject of wound infection, not only in relation to surgical diseases, but to child-bed fever, forms now one of the most brilliant chapters in the history of Preventive Medicine.
II.
Pasteur was early impressed with the analogies between fermentation and putrefaction48 and the infectious diseases, and in 1863 he assured the French Emperor that his ambition was “to arrive at the knowledge of the causes of putrid and contagious49 diseases.” After a study upon the diseases of wines, which has had most important practical bearings, an opportunity came of the very first importance, which not only changed the whole course of his career, but had great influence in the development of medical science. A disease of the silkworm had, for some years, ruined one of the most important industries of France, and in 1865 the Government asked Pasteur to give up the laboratory work and teaching, and to devote his whole energies to the task of investigating it. The story of the brilliant success which followed years of application to the problem will be read with deep interest by every student of science. It was the first of his victories in the application of the experimental methods of a trained chemist to the{x} problems of biology, and it placed his name high in the group of the most illustrious benefactors50 of practical industries.
The national tragedy of 1870-2 nearly killed Pasteur. He had a terrible pilgrimage to make in search of his son, a sergeant51 in Bourbaki’s force. “The retreat from Moscow cannot have been worse than this,” said the savant. In October, 1868, he had had a stroke of paralysis52, from which he recovered in a most exceptional way, as it seemed to have diminished neither his enthusiasm nor his energy. In a series of studies on the diseases of beer, and on the mode of production of vinegar, he became more and more convinced that these studies on fermentation had given him the key to the nature of the infectious diseases. It is a remarkable53 fact that the distinguished54 English philosopher of the seventeenth century, the man who more than any one else of his century appreciated the importance of the experimental method, Robert Boyle, had said that he who could discover the nature of ferments55 and fermentation, would be more capable than anyone else of explaining the nature of certain diseases. The studies on spontaneous generation, and Lister’s application of the germ theory to the treatment of wounds, had aroused the greatest interest in the medical world, and Villemin, in a series of most brilliant experiments, had demonstrated the infectivity of tuberculosis56. An extraordinary opportunity now offered for the study of a widespread epidemic21 disease, known as anthrax, which in many parts of France killed from 25 to 30 per cent. of the sheep and cattle, and which in parts of Europe had been pandemic, attacking both man and beast. As far back as 1838 minute rods had been noted in the blood of animals which had died from the disease; and in 1863 Devaine thought that these little bodies, which he called bacteridia, were the cause of the disease. In 1876 a young German district physician, Robert Koch, began a career, which in interest and importance rivals that of the subject of this memoir57. Koch confirmed in every point the old researches of Devaine; but he did much more, and for the first time isolated58 the organism in pure culture outside the body, grew successive generations, showed the{xi} remarkable spore60 formation, and produced the disease artificially in animals by inoculating61 with the cultures. Pasteur confirmed these results, and in the face of extraordinary opposition succeeded in convincing his opponents. Out of this study came a still more important discovery, namely, that it was possible so to attenuate62 or weaken the virus or poison that the animal could be inoculated63, and have a slight attack, recover, and be protected against the disease. More than eighty years had passed since, on May 14th, 1796, Jenner, with a small bit of virus taken from a cow-pox on the hand of the milkmaid, Sarah Newlme, had vaccinated64 a child, and thus proved that a slight attack of one disease would protect the body from disease of a similar character. It was an occasion famous in the history of medicine, when, in the spring of 1881, at Melun, at the farmyard of Pouilly le Fort, the final test case was determined65, and the flock of vaccinated sheep remained well, while every one of the unvaccinated, inoculated from the same material, had died. It was indeed a great triumph.
The studies on chicken cholera66, yellow fever, and on swine plague helped to further the general acceptance of the germ theory. I well remember at the great meeting of the International Congress in 1881, the splendid reception accorded to the distinguished Frenchman, who divided with Virchow the honours of the meeting. Finally came the work upon one of the most dreaded67 of all diseases—hydrophobia, an infection of a most remarkable character, the germ of which remains69 undiscovered. The practical results of Pasteur’s researches have given us a prophylactic70 treatment of great efficacy. Before its introduction the only means of preventing the development of the disease was a thorough cauterisation of the disease wound within half an hour after its infliction71. Pasteur showed that animals could be made immune to the poison, and devised a method by which the infection conveyed by the bite could be neutralised. Pasteur Institutes for the treatment of hydrophobia have been established in different countries, and where the disease is widely prevalent have been of the greatest benefit. Except at the London Congress, the only occasion{xii} on which I saw the great master was in 1891 or 1892, when he demonstrated at the Institute to a group of us the technique of the procedure, and then superintended the inoculations of the day. A large number of persons are treated in the course of the year; a good many, of course, have not been bitten by mad dogs; but a very careful classification is made:—
(a) Includes persons bitten by dogs proved experimentally to have been mad.
(b) Persons bitten by dogs declared to be mad by competent veterinary surgeons.
(c) All other cases.
The mortality even in Class A is very slight, though many patients are not brought until late. Incidentally it may be remarked the lesson of this country in its treatment of hydrophobia is one of the most important ever presented in connection with an infectious disease. There are no Pasteur Institutes; there are no cases. Why? The simple muzzling72 order has prevented the transmission of the disease from dog to dog, and once exterminated73 in the dog, the possibility of the infection in man had gone. In 1888 the crowning work of Pasteur’s life was the establishment of an Institute to serve as a centre of study on contagious disease, and a dispensary for the treatment of hydrophobia, which is to-day the most important single centre of research in the world. The closing years of his life were full of interest in the work of his colleagues and assistants, and he had the great satisfaction of participating, with his assistant Roux, in another great victory over the dread68 scourge4, diphtheria. Before his death in 1895 he had seen his work prosper74 in a way never before granted to any great discoverer. To no one man has it ever been given to accomplish work of such great importance for the well-being75 of humanity. As Paul Bert expressed it in the report to the French Government, Pasteur’s work constitutes three great discoveries, which may be thus formulated76. 1. Each fermentation is produced by the development of a special microbe.
2. Each infectious disease is produced by the development within the organism of a special microbe.{xiii}
3. The microbe of an infectious disease culture, under certain detrimental77 condition is attenuated78 in its pathogenic activity; from a virus it has become a vaccine79.
In an address delivered in Edinburgh by Sir James Simpson in 1853, in which he extolled80 the recent advancement81 of physic, occur these words:—“I do not believe, that, at the present moment, any individual in the profession, who, in surgery or in midwifery, could point out some means of curing—or some prophylactic means of averting82 by antecedent treatment—the liability to these analogous83 or identical diseases—viz., surgical or puerperal fever—such a fortunate individual would, I say, make, in relation to surgery and midwifery, a greater and more important discovery than could possibly be attained84 by any other subject of investigation36. Nor does such a result seem hopelessly unattainable.” Little did he think that the fulfilment of these words was in the possession of a young Englishman who had just gone to Edinburgh as an assistant to his colleague, Professor Syme. Lister’s recognition of the importance of Pasteur’s studies led to the fulfilment within this generation of the pious85 hope expressed by Simpson. In Institutions and Hospitals surgical infection and puerperal fevers are things of the past, and for this achievement if for nothing else, the names of Louis Pasteur and Joseph Lister will go down to posterity86 among those of the greatest benefactors of humanity.
III.
In his growth the man kept pace with the scientist—heart and head held even sway in his life. To many whose estimate of French character is gained from “yellow” literature this story will reveal the true side of a great people, in whom filial piety87, brotherly solicitude88, generosity89, and self-sacrifice are combined with a rare devotion to country. Was there ever a more charming picture than that of the family at D?le! Napoleon’s old sergeant, Joseph Pasteur, is almost as interesting a character as his illustrious son; and we follow the joys and sorrows of the home with unflagging attention. Rarely{xiv} has a great man been able to pay such a tribute to his father as that paid by Pasteur:—“For thirty years I have been his constant care, I owe everything to him.”
This is a biography for young men of science, and for others who wish to learn what science has done, and may do, for humanity. From it may be gleaned90 three lessons.
The value of method, of technique, in the hands of a great master has never been better illustrated91. Just as Harvey, searching out Nature by way of experiment, opened the way for a study of the functions of the body in health, so did Pasteur, bringing to the problems of biology the same great organon, shed a light upon processes the nature of which had defied the analysis of the keenest minds. From Dumas’s letter to Pasteur, quoted in Chapter VI., a paragraph may be given in illustration:—“The art of observation and that of experiment are very distinct. In the first case, the fact may either proceed from logical reasons or be mere47 good fortune; it is sufficient to have some penetration92 and the sense of truth in order to profit by it. But the art of experimentation93 leads from the first to the last link of the chain, without hesitation94 and without a blank, making successive use of Reason, which suggests an alternative, and of Experience, which decides on it, until, starting from a faint glimmer8, the full blaze of light is reached.” Pasteur had the good fortune to begin with chemistry, and with the science of crystallography, which demanded extraordinary accuracy, and developed that patient persistence95 so characteristic of all his researches.
In the life of a young man the most essential thing for happiness is the gift of friendship. And here is the second great lesson. As a Frenchman, Pasteur had the devotion that marks the students of that nation to their masters, living and dead. Not the least interesting parts of this work are the glimpses we get of the great teachers with whom he came in contact. What a model of a scientific man is shown in the character of Biot, so keenly alive to the interests of his young friend, whose brilliant career he followed with the devotion of a second father. One of the most touching96 incidents recorded{xv} in the book relates to Pasteur’s election to the Academy of Sciences:—“The next morning when the gates of the Montparnasse cemetery97 were opened, a woman walked towards Biot’s grave with her hands full of flowers. It was Mme. Pasteur who was bringing them to him ... who had loved Pasteur with so deep an affection.” Pasteur looked upon the cult59 of great men as a great principle in national education. As he said to the students of the University of Edinburgh:—“Worship great men”;[1] and this reverence98 for the illustrious dead was a dominant element in his character, though the doctrines99 of Positivism seemed never to have had any attraction for him. A dark shadow in the scientific life is often thrown by a spirit of jealousy100, and the habit of suspicious, carping criticism. The hall-mark of a small mind, this spirit should never be allowed to influence our judgment101 of a man’s work, and to young men a splendid example is here offered of a man devoted102 to his friends, just and generous to his rivals, and patient under many trying contradictions and vexatious oppositions103.
And the last great lesson is humility104 before the unsolved problems of the Universe. Any convictions that might be a comfort in the sufferings of human life had his respectful sympathy. His own creed105 was beautifully expressed in his eulogy106 upon Littré:—“He who proclaims the existence of the Infinite, and none can avoid it—accumulates in that affirmation more of the supernatural than is to be found in all the miracles of all the religions; for the notion of the Infinite presents that double character that it forces itself upon us and yet is incomprehensible. When this notion seizes upon our understanding, we can but kneel.... I see everywhere the inevitable107 expression of the Infinite in the world; through it, the supernatural is at the bottom of every heart. The idea of God is a form of the idea of the Infinite. As long as the mystery of the Infinite weighs on human thought, temples will be erected108 for the worship of the Infinite, whether God is called Brahma, Allah, Jehovah, or Jesus; and on the pavement{xvi} of those temples, men will be seen kneeling, prostrated109, annihilated110 in the thought of the Infinite.” And modern Pantheism has never had a greater disciple111, whose life and work set forth112 the devotion to an ideal—that service to humanity is service to God:—“Blessed is he who carries within himself a God, an ideal, and who obeys it: ideal of art, ideal of science, ideal of the gospel virtues113, therein lie the springs of great thoughts and great actions; they all reflect light from the Infinite.”
The future belongs to Science. More and more she will control the destinies of the nations. Already she has them in her crucible114 and on her balances. In her new mission to humanity she preaches a new gospel. In the nineteenth century renaissance115 she has had great apostles, Darwin, for example, whose gifts of heart and head were in equal measure, but after re-reading for the third or fourth time the Life of Louis Pasteur, I am of the opinion, expressed recently by the anonymous116 writer of a beautiful tribute in the Spectator, “that he was the most perfect man who has ever entered the Kingdom of Science.”
William Osler.
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1 par | |
n.标准,票面价值,平均数量;adj.票面的,平常的,标准的 | |
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2 ferment | |
vt.使发酵;n./vt.(使)激动,(使)动乱 | |
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3 scourged | |
鞭打( scourge的过去式和过去分词 ); 惩罚,压迫 | |
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4 scourge | |
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adv.有求知欲地;好问地;奇特地 | |
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6 malaria | |
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adv.完全地,全部地,彻底地;充分地 | |
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9 haphazard | |
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11 morbid | |
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12 anatomy | |
n.解剖学,解剖;功能,结构,组织 | |
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13 colossal | |
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14 extraordinarily | |
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15 irrational | |
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16 scourges | |
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17 pestilences | |
n.瘟疫, (尤指)腺鼠疫( pestilence的名词复数 ) | |
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18 advent | |
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19 catching | |
adj.易传染的,有魅力的,迷人的,接住 | |
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20 epidemics | |
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21 epidemic | |
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22 spoke | |
n.(车轮的)辐条;轮辐;破坏某人的计划;阻挠某人的行动 v.讲,谈(speak的过去式);说;演说;从某种观点来说 | |
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23 contagion | |
n.(通过接触的疾病)传染;蔓延 | |
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n. 酿造, 一次酿造的量 动词brew的现在分词形式 | |
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25 noted | |
adj.著名的,知名的 | |
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26 yeast | |
n.酵母;酵母片;泡沫;v.发酵;起泡沫 | |
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27 lactic | |
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28 alcoholic | |
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30 strictly | |
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31 dominant | |
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32 warfare | |
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34 opposition | |
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35 putrid | |
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36 investigation | |
n.调查,调查研究 | |
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37 investigations | |
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38 transformation | |
n.变化;改造;转变 | |
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39 boons | |
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40 surgical | |
adj.外科的,外科医生的,手术上的 | |
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41 decomposition | |
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42 applied | |
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43 philosophic | |
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44 thoroughly | |
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45 gaseous | |
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46 constituents | |
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47 mere | |
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48 putrefaction | |
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49 contagious | |
adj.传染性的,有感染力的 | |
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50 benefactors | |
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52 paralysis | |
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54 distinguished | |
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55 ferments | |
n.酵素( ferment的名词复数 );激动;骚动;动荡v.(使)发酵( ferment的第三人称单数 );(使)激动;骚动;骚扰 | |
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56 tuberculosis | |
n.结核病,肺结核 | |
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60 spore | |
n.(无花植物借以繁殖的)孢子,芽胞 | |
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61 inoculating | |
v.给…做预防注射( inoculate的现在分词 ) | |
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62 attenuate | |
v.使变小,使减弱 | |
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63 inoculated | |
v.给…做预防注射( inoculate的过去式和过去分词 ) | |
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64 vaccinated | |
[医]已接种的,种痘的,接种过疫菌的 | |
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65 determined | |
adj.坚定的;有决心的 | |
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66 cholera | |
n.霍乱 | |
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67 dreaded | |
adj.令人畏惧的;害怕的v.害怕,恐惧,担心( dread的过去式和过去分词) | |
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68 dread | |
vt.担忧,忧虑;惧怕,不敢;n.担忧,畏惧 | |
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69 remains | |
n.剩余物,残留物;遗体,遗迹 | |
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70 prophylactic | |
adj.预防疾病的;n.预防疾病 | |
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71 infliction | |
n.(强加于人身的)痛苦,刑罚 | |
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72 muzzling | |
给(狗等)戴口套( muzzle的现在分词 ); 使缄默,钳制…言论 | |
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73 exterminated | |
v.消灭,根绝( exterminate的过去式和过去分词 ) | |
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74 prosper | |
v.成功,兴隆,昌盛;使成功,使昌隆,繁荣 | |
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75 well-being | |
n.安康,安乐,幸福 | |
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76 formulated | |
v.构想出( formulate的过去式和过去分词 );规划;确切地阐述;用公式表示 | |
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77 detrimental | |
adj.损害的,造成伤害的 | |
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78 attenuated | |
v.(使)变细( attenuate的过去式和过去分词 );(使)变薄;(使)变小;减弱 | |
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79 vaccine | |
n.牛痘苗,疫苗;adj.牛痘的,疫苗的 | |
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80 extolled | |
v.赞颂,赞扬,赞美( extol的过去式和过去分词 ) | |
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81 advancement | |
n.前进,促进,提升 | |
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82 averting | |
防止,避免( avert的现在分词 ); 转移 | |
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83 analogous | |
adj.相似的;类似的 | |
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84 attained | |
(通常经过努力)实现( attain的过去式和过去分词 ); 达到; 获得; 达到(某年龄、水平、状况) | |
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85 pious | |
adj.虔诚的;道貌岸然的 | |
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86 posterity | |
n.后裔,子孙,后代 | |
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87 piety | |
n.虔诚,虔敬 | |
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88 solicitude | |
n.焦虑 | |
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89 generosity | |
n.大度,慷慨,慷慨的行为 | |
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90 gleaned | |
v.一点点地收集(资料、事实)( glean的过去式和过去分词 );(收割后)拾穗 | |
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91 illustrated | |
adj. 有插图的,列举的 动词illustrate的过去式和过去分词 | |
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92 penetration | |
n.穿透,穿人,渗透 | |
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93 experimentation | |
n.实验,试验,实验法 | |
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94 hesitation | |
n.犹豫,踌躇 | |
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95 persistence | |
n.坚持,持续,存留 | |
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96 touching | |
adj.动人的,使人感伤的 | |
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97 cemetery | |
n.坟墓,墓地,坟场 | |
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98 reverence | |
n.敬畏,尊敬,尊严;Reverence:对某些基督教神职人员的尊称;v.尊敬,敬畏,崇敬 | |
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99 doctrines | |
n.教条( doctrine的名词复数 );教义;学说;(政府政策的)正式声明 | |
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100 jealousy | |
n.妒忌,嫉妒,猜忌 | |
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101 judgment | |
n.审判;判断力,识别力,看法,意见 | |
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102 devoted | |
adj.忠诚的,忠实的,热心的,献身于...的 | |
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103 oppositions | |
(强烈的)反对( opposition的名词复数 ); 反对党; (事业、竞赛、游戏等的)对手; 对比 | |
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104 humility | |
n.谦逊,谦恭 | |
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105 creed | |
n.信条;信念,纲领 | |
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106 eulogy | |
n.颂词;颂扬 | |
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107 inevitable | |
adj.不可避免的,必然发生的 | |
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108 ERECTED | |
adj. 直立的,竖立的,笔直的 vt. 使 ... 直立,建立 | |
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109 prostrated | |
v.使俯伏,使拜倒( prostrate的过去式和过去分词 );(指疾病、天气等)使某人无能为力 | |
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110 annihilated | |
v.(彻底)消灭( annihilate的过去式和过去分词 );使无效;废止;彻底击溃 | |
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111 disciple | |
n.信徒,门徒,追随者 | |
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112 forth | |
adv.向前;向外,往外 | |
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113 virtues | |
美德( virtue的名词复数 ); 德行; 优点; 长处 | |
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114 crucible | |
n.坩锅,严酷的考验 | |
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115 renaissance | |
n.复活,复兴,文艺复兴 | |
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116 anonymous | |
adj.无名的;匿名的;无特色的 | |
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