The medical history of the eighteenth century affords but a meagre result, notwithstanding the brilliant talents and indefatigable6 industry of the famous men who devoted7 their energies to the healing art. Their great aim was to create systems of medicine which should be philosophical8 and complete.
It is not only in what is strictly9 the art of healing that the members of the medical profession have ever been amongst the greatest benefactors10 of the world, but in what are known as the accessory sciences many of the most distinguished11, enlightened, and self-sacrificing of the heroes of science have been affiliated12 to the profession of medicine. Not only the heroes, but the martyrs13 of medicine, crowd the scientific calendar. The seventeenth and eighteenth centuries were fertile in the efforts to apply the results of discoveries in the physical sciences to the relief of human suffering. If these efforts were but partially14 successful, so far as medicine—considered apart from surgery—was concerned, it was not in consequence of less industry in that department, but because speculation15 and theorising about the causes of disease monopolised the attention which, if devoted to observation of facts, would have been fertile in result. Schools, Systems, and Sects17 were the chief product of the medical activity of the eighteenth century. Although not perhaps of much direct benefit to medicine, indirectly18 the study of the sciences accessory to it must have been of considerable benefit as an educational factor in the training of the intellect of physicians.
The Great Schools of Medical Theory.
Whewell, in his History of Scientific Ideas,990 classifies the successive biological hypotheses under the heads: (1) The Mystical School;419 (2) The Iatro-Chemical School; (3) The Iatro-Mathematical School; (4) The Vital-Fluid School; (5) The Psychical19 School.
The Mystical School found its most distinguished representative in Paracelsus; it derived20 its doctrine21 of the Macrocosm and the Microcosm from the Neoplatonists, and was largely imbued22 with alchemy and magic, the doctrines23 of the Cabala and the fanciful interpretations24 of the Bible. Later Paracelsists, Rosicrucians, and other speculators of the same character, such as Sir Kenelm Digby, brought the Mystical School of Medicine down to the seventeenth century. Our modern Theosophists are striving to restore much of the mystical teaching of Paracelsus and his followers26. Again we meet the “astral bodies,” “the elementary spirits,” the cabalistic interpretations of the Bible, and the astrological absurdities27 of a pre-scientific period.
The Iatro-Chemical School really arose from Paracelsus, who amongst many absurdities held much important truth. Sprengel indicates Libavius of Saxony as the person who first cultivated chemistry apart from theosophy, and he names Angelus Sala as his successor. Lemery, in the middle of the seventeenth century, began to reform pharmaceutical28 chemistry. After Paracelsus chemistry became an indispensable study to every physician. Our word tartar, the scale which forms on the teeth, is of Paracelsian origin. He taught that the basis of all diseases was a thickening of the juices and the formation of earthy matter, which he called Tartarus, because it burns like the fire of hell. After Paracelsus we have Van Helmont, a true chemical discoverer who sought in chemistry a theory of disease of which his doctrine of fermentation in the body holds an important place. Next we have Sylvius, with his doctrine of the opposition30 of acid and alkali. Digestion31 he considered a process of fermentation or effervescence of the acid of the saliva32 and pancreatic juice with the alkali of the gall33. When either the acid or the alkali predominated, disease was supposed to follow. The human body was regarded as a laboratory, the stomach as a sort of test tube. Boyle made objections to the doctrines of this school, and Herman Conring taught that the proper place of chemistry was not in physiology34 and pathology, but in pharmacy35.
Viridet of Geneva endeavoured to prove that the fluids of the body are either acid or alkaline by experiment. Raimond Vieussens declared that he had discovered an acid in the blood and a ferment29 in the stomach. Hecquet opposed him, and said that digestion was not a process of fermentation, but of trituration. Pitcairn in England, Bohn and Hoffman in Germany, and Boerhaave in Holland opposed the iatro-chemists, and proved by observation that digestion is not fermentation, and that the acid and alkali theories of disease supported by Sylvius were420 false. By the influence and authority of these eminent37 physicians, the reign38 of the chemical school of physiology was overturned. The great fault of the iatro-chemists was their neglect of the effect of the solids of the animal body; they assimilated the work of the physician, as Whewell says, to that of the vintner or the brewer39.
The Iatro-Mathematical or Mechanical School attacked, defeated, and superseded40 the iatro-chemists. According to this sect16, the human body is a mere41 machine. Whewell explains that the Mechanical Physiologists came into existence in consequence of the splendid results obtained by the schools of Galileo and Newton. It was not so much the exposure of the weaknesses of the chemical physiology as the effects produced upon the world by the explanation of so many of the phenomena42 of the external universe by the men who had revolutionized astronomy by their discoveries; it was naturally hoped that that which served to explain the great world of matter might also elucidate43 the little world of man. Whewell divides the school into two parts—the Italian and the Cartesio-Newtonian sect. The Italian calculated and analysed the properties of the animal body which are undoubtedly44 purely45 mechanical, the Cartesio-Newtonians went much further than this and introduced many baseless hypotheses. The Italians occupied themselves with such calculations as the force of muscles and the hydraulics of the animal fluid. Borelli was the first great investigator47 on these lines; his work De Motu Animalium (Rome, 1680), treats of the forces and action of the bones and muscles. John and Daniel Bernouelli and Henry Pemberton pursued the same line of research. The principles of hydrostatics were brought to bear on the questions of the blood pressure and the breath. Keill endeavoured to estimate the velocity48 of the blood. The other school occupied itself with the corpuscular hypothesis in physiology. The organs were considered as a species of sieves49. Both Newton and Descartes sought to explain physiology on a theory of round particles passing through cylindrical50 tubes, pyramidal ones through pores of a triangular51 shape, cubical through square openings. The diameter and curves of the different vessels52 formed subjects of calculations, and Bellini, Donzellini, and Guglielmini in Italy, Perrault and Dodart in France, Cole, Keill, and Jurin in England, devoted themselves to their study.991
The investigation53 of the size and shape of the particles of the fluids, and the diameter and form of the invisible vessels, formed a large part of the physiology of the beginning of the eighteenth century. Cheyne thought that fevers of the acute sort arise from glandular54 obstruction;421 and Mead55, the royal physician and friend of Newton, explained the action of poisons on mechanical principles. The error of this school, as Whewell explains, lay in considering the animal frame as a lifeless compound of canals, cords and levers; the physicians, to its adherents56, were merely hydraulic46 engineers. Some iatro-mathematicians58 were, in fact, at the same time teachers both of engineering and medicine.992
The Vital-Fluid School. The mechanical explanation of the motions of the animal body may satisfy some observers up to a certain point; there, however, they must confess their theory fails them. How does motion originate in the living frame? Friedrich Hoffman, of Halle (b. 1660), assumed a principle, material, yet of a higher kind than the adherents of the mechanical sect were inclined to recognise. This principle is exceedingly subtle, and is endued59 with great energy. It is the ether diffused60 through all nature, and which has its seat in the brain of animals and acts upon the body through the nerves. This vital fluid operates by laws which at one time were explained on the principles of a higher mechanics, of which we know little, and at another on metaphysical grounds, of which we know less. Naturally the discoveries connected with electricity imported a new element into these speculations61. The vital principle was then held to be a modification62 of the electric fluid. John Hunter discerned it in the blood. Cuvier believed the vital fluid to be nervous. The objections to the doctrine of a vital fluid “as one uniform material agent pervading63 the organic frame,” are many. If the vital principle be the same in every part of the body, how does it happen that the secretions64 are all so different? How does the blood under the same influence furnish all the different fluids produced by the glands66? How is it the liver secretes67 bile, the kidneys their peculiar68 fluid, the lachrymal gland36 the tears? The hypothesis of a vital fluid really explains nothing.
The Psychical School held the doctrine of an immaterial vital principle. This is at least as old as Aristotle,993 who attributes the cause of motion to the soul. According to that philosopher the soul has different parts: the nutritive or vegetative, the sensitive, and the rational. Stahl, the great discoverer in chemistry, opposed the physiological69 theories of Hoffman, and declared that there is something in living bodies which cannot be accounted for by mechanics or chemistry. “All motion,” according to him, “is a spiritual act.” Nutrition and secretion65 belong to the operations of the soul; but he overlooked the fact that these are not peculiar to animals, but are characteristics of vegetables, which have no soul. Cheyne and Mead, Pater422field and Whytt in England inclined to Stahl’s views. Boissier de Sauvages defended them in France. Hoffman and afterwards Haller opposed them, the latter inventing the theory of Irritability70.
Boerhaave (1668-1738), professor of medicine at Leyden, was a man of varied71 and profound erudition, conversant72 with the teaching of the ancient philosophers and the Greek and Arabian physicians; he was in addition fully73 conversant with all the discoveries connected with the healing art down to his own time. Beyond this he was a natural philosopher, chemist, botanist74, and anatomist, and an indefatigable experimentalist. In teaching medicine he simplified its study as much as possible by rejecting the absurd and useless speculations which encumbered75 it, and putting in their place the facts which he believed his own experience and observation had enabled him to ascertain76. He published his system of medicine in two volumes, one entitled the Instructions or Theory and the other the Aphorisms77 or Practice of Medicine. “These short treatises78,” says Dr. Thomson,994 “which gave to medicine a more systematic80 form than it had previously81 exhibited, are remarkable82 for brevity, perspicuity83, and elegance84 of style, for great condensation85 of ideas, and for the number of important facts which they contain relative to the healthy and diseased states of the human economy.” The genius of Boerhaave raised the medical school of Leyden to the highest distinction. Princes in all countries sent him pupils; Peter the Great took lessons in medicine from him, and so great was his reputation that when a Chinese mandarin86 directed a letter to him, “To the illustrious Boerhaave, physician in Europe,” it was duly delivered. He held the study of Mind to form an important part of physiology. He taught that the change produced upon the extremity87 of the sentient88 nerve must be transmitted by the nerve to the brain before sensation can be produced. He considered the nerves to be hollow undulatory canals. He also held that each of the senses has its distinct seat in the common sensory89 or brain. His lectures on the mental faculties90 are full of varied and curious information. Considering the human body as a combination of various machines arranged in one harmonious91 whole, he endeavoured to explain its phenomena in health and disease on the principles of natural philosophy and chemistry to the almost entire exclusion92 of vital forces, which, however, he did not reject. He denied that all medical phenomena are to be explained upon mechanical principles. He lamented93 that “physiological subjects are usually handled either by mathematicians unskilful in anatomy, or by anatomists who are not versed95 in mathematics.” Yet his system of physiology embraced423 but a poor conception of the mystery of life. He says, “Let anatomy faithfully describe the parts and structure of the body; let the mechanician apply his particular science to the solids; let hydrostatics explain the laws of fluids in general, and hydraulics their actions, as they move through given canals; and lastly, let the chemist add to all these whatever his art, when fairly and carefully applied96, has been able to discover; and then, if I am not mistaken, we shall have a complete account of medical physiology.”
It is to Boerhaave that we owe the peculiar chemical idea of affinity97, that mutual98 virtue99 by which one chemical substance loves, unites with, and holds the other (amat, unit, retinet). He called it love. “We are here to imagine, not mechanical action, not violent impulse, not antipathy100, but love, at least if love be the desire of uniting.” It is to Boerhaave, therefore, we are indebted for a view of chemical affinity which enables us to comprehend all chemical changes.995
The idea of affinity as marriage naturally leads to analysis as divorce. Thus affinity, imperfectly understood before the time of Boerhaave, made analysis possible. One of the first to express this conviction was Dr. Mayow, who published his Medico-Physical Tracts101 in 1674. He shows how an acid and an alkali lose their properties by combination, a new substance being formed not at all resembling either of the ingredients. He explains that, “although these salts thus mixed appear to be destroyed, it is still possible for them to be separated from each other, with their power still entire.”996
George Ernest Stahl (1660-1734), chemist, was professor of medicine at Halle (1694) and physician to the King of Prussia (1716). He opposed materialism102, and substituted “animism,” explaining the symptoms of disease as efforts of the soul to get rid of morbid103 influences. Stahl’s “anima” corresponds to Sydenham’s “nature” in a measure, and has some relationship to the Archeus of Paracelsus and Van Helmont. Stahl was the author of the “phlogiston” theory in chemistry, which in its time has had important influence on medicine. Phlogiston was a substance which he supposed to exist in all combustible104 matters, and the escape of this principle from any compound was held to account for the phenomenon of fire. According to Stahl, diseases arise from the direct action of noxious105 powers upon the body; and from the reaction of the system itself endeavouring to oppose and counteract106 the effects of the noxious powers, and so preserve and repair itself.997 He did not consider diseases, therefore, pernicious in them424selves, though he admitted that they might become so from mistakes made by the soul in the choice, or proportion of the motions excited to remove them, or the time when these efforts are made. Death, according to this theory, is due to the indolence of the soul, leading it to desist from its vital motions, and refusing to continue longer the struggle against the derangements of the body.998 Here we have the “expectant treatment” so much in vogue107 with many medical men. “Trusting to the constant attention and wisdom of nature,” they administered inert108 medicines as placebos109, while they left to nature the cure of the disease. But they neglected the use of invaluable110 remedies such as opium111 and Peruvian bark, for which error it must be admitted they atoned112 by discountenancing bleeding, vomiting113, etc.999 Stahl’s remedies were chiefly of the class known as “Antiphlogistic,” or antefebrile.
De Sauvages (1706-1767), the French physicist114, was a disciple115 of Stahl, and adopted his theory of soul as the cause of the mechanical action of the body. He invented a system of classifying diseases under the title of Nosologia Methodica, founded on the principles of natural history.
Friedrich Hoffman (1660-1742) was a fellow-student with Stahl at Jena. He was the author of a system of medicine in some respects original. He distinguished in the human economy three principal agents: Nature, or the Organic Body; the Sentient Soul; and the Rational Soul; corresponding to the classification of the Scripture116 of body, soul, and spirit—a classification which originated doubtless in Indian philosophy. Hoffman did not admit with Stahl that the organic functions of the human body depend on the agency of an intelligent soul or any immaterial agent whatsoever117, but are merely mechanical and chemical properties of the elements which compose our bodies. The functions most essential to life he considered to be the circulatory, secretory118, and excretory motions, and these seemed to him to depend upon the dilating119 and contracting powers of the muscular fibres of the vascular120 system. These powers then he held to be the cause of the organic functions which depend on the animal spirits, an ethereal fluid contained in the nerves and the blood.1000
Hoffman first made known the virtues121 of the Seidlitz waters; he also invented a nostrum122 which was popular for a long time, and called425 “Hoffman’s Anodyne123 Liquor.”
Physicians.
Archibald Pitcairn, M.D. (1652-1713), was a famous physician of Edinburgh. In 1692 he occupied a professor’s chair at Leyden with great distinction. Among his pupils were Mead and Boerhaave, who both attributed much of their skill to his tuition. On his return to Edinburgh he greatly interested himself in improving the teaching of anatomy. He begged the Town Council to permit the dissection124 of the bodies of paupers125; and though the chief surgeons of the place did all they could to oppose his efforts, they were successful, and Pitcairn had the credit of laying the foundation of the great Edinburgh school of medicine. He insisted on the strict adherence126 to Bacon’s method of attending to facts of experience and observation. “Nothing,” he said, “more hinders physic from being improved than the curiosity of searching into the natural causes of the effects of medicines. The business of men is to know the virtues of medicines; but to inquire whence they have that power is a superfluous127 amusement, since nature lies concealed129. A physician ought therefore to apply himself to discover by experience the effects of medicines and diseases, and reduce his observations into maxims131, and not needlessly fatigue132 himself by inquiring into their causes, which are neither possible nor necessary to be known. If all physicians would act thus, we should not see physic divided into so many sects.” In his Dissertations133 (1701) he discusses the application of geometry to physic, the circulation of the blood, the cure of fevers by purgation, and the effects of acids and alkalis in medicine. A learned and skilful94 physician, an accomplished134 mathematician57, and a thorough classical scholar, he was not discreet135 in his political utterances136. His library was purchased by Peter the Great of Russia.
John Radcliffe, M.D. (1650-1714), was famous for “his magnificent regard for the advancement137 of learning and science.” The Radcliffe infirmary and observatory138 at Oxford139 were built from funds bequeathed by him.
Sir Hans Sloane, M.D. (1660-1753), was a physician whose noble museum and library were the foundation of the British Museum.
Sir Richard Blackmore, M.D. (1650-1729), wrote on inoculation for small-pox, on consumption, gout, rheumatism140, scrofula, diabetes141, jaundice, etc.
Walter Needham, M.D. (died 1691), made important investigations142 in the anatomy of the f?tus, and the changes of the pregnant uterus.
Clopton Havers, M.D. (died 1702), was the author of a standard426 work on the bones, certain canals of which were called after him Haversian canals.
James Douglas, M.D. (1675-1742), was an excellent anatomist, who was one of the first to demonstrate from anatomy that the high operation for stone might be safely performed. He was a skilful accoucheur, an accomplished botanist, and a man of letters. Pope mentions him in the Dunciad, and in a note describes him as a physician of great learning and no less taste. He wrote several works, the most famous of which is Myographi? Comparat? Specimen143; or a comparative description of all the muscles in a man and in a quadruped; added is an account of the muscles peculiar to a woman. London, 1707.
William Cullen, M.D. (1710-1790), was the first professor in Great Britain to deliver his lectures in the English language.1001 He was appointed lecturer on chemistry at Glasgow University in 1746, and in 1751 was chosen regius professor of medicine. In 1756 he became professor of chemistry in the University of Edinburgh; in 1760 he was made lecturer on materia medica. Dr. Cullen earned great distinction as a lecturer on medicine; he opposed the teaching of Boerhaave and the principles of the humoral pathology, founding his own teaching on that of Hoffman. His system was to a great extent based on the new physiological doctrine of irritability as taught by Haller.
He attached great importance to nervous action in the induction144 of disease, considering even gout as a neurosis.
His First Lines of the Practice of Physic was long exceedingly popular, but his fame as a medical writer rests on his Nosology, or Classification of Diseases. In all his labours Dr. Cullen aimed at the practical rather than the theoretical. “My business is not,” he remarks,1002 “so much to explain how this and that happens, as to examine what is truly matter of fact.” “My anxiety is not so much to find out how it happens as to find out what happens.” Cullen invented no ingenious hypothesis, rather he new-modelled the whole practice of medicine; “he defined and arranged diseases with an unrivalled accuracy, and reduced their treatment to a simplicity145 formerly146 unknown.”1003
James Gregory, M.D. (1758-1822), exercised the greatest influence on the progress of medicine in England. As the successor of Cullen, and as the author of the famous Conspectus Medicin? Theoretic?, the name of Gregory, borne by many ornaments147 of British science, became still more distinguished.
Sir Gilbert Blane, M.D. (born 1747), rendered important medical services to the State by his researches on the diseases incident to sea427men. He banished148 scurvy149 from the fleet by his arrangements for provisioning ships on foreign stations, particularly by making lemon juice a regular ingredient of diet.
Sir William Watson, M.D. (1715-1787), was a devoted botanist and student of electricity. His electrical researches raised him to a position of European fame. He was the first in England who succeeded in igniting spirit of wine by electricity; he was the first to note the different colour of the spark, as drawn150 from different bodies; and his researches in the power and accumulation of electricity, the nature of its conductors, etc., qualified151 him to take part in the experiments carried out in 1747 and 1748, by which the “electric current was extended to four miles in order to prove the velocity of its transmission.”1004 The doctor’s house in Aldersgate Street was long the resort of the most distinguished men of science in Europe. He was not less the benign152 and generous friend to the poor and suffering, than the ardent153 investigator of the secrets of Nature. His work Experiments and Observations on Electricity is quite a remarkable production considering the age in which it was published (1768).
Robert Willan, M.D. (1757-1812), was the founder154 of the science of skin diseases in England. His attention was directed in 1784 to the elementary forms of eruption155, and on this basis he erected156 his magnum opus, The Description and Treatment of Cutaneous Diseases (1798).
John Brown (1735-1788), was a systematizer of medicine, whose popularity was even continental157. He endeavoured to explain the processes of life and disease and the principles of cure upon one simple idea, the property of “excitability.” The “exciting powers” are the external forces, and the functions of the body are stimulants158, so that “the whole phenomena of life, health as well as disease, consist in stimulus159 and nothing else.” Diseases he divided as sthenic, attended with preternatural excitement, and asthenic, characterized by debility.
Ninety-seven per cent. of all diseases, he declared, require a “stimulating treatment.” One good result of this theory was that it introduced a milder treatment of disease than the bleeding and purging160 doctors of his time advocated. The theory was called the Brunonian, and received greater attention in Italy than in England.
John Morgan, M.D. (1736-1789), was born in Philadelphia. He wrote an essay on his graduation at Edinburgh (1763), wherein “he maintained that pus is a secretion from the vessels, and in this view anticipated John Hunter.”1005
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Robert James, M.D. (1703-1776), was the inventor of the celebrated161 fever-powder which bears his name.
Francis de Valingen, M.D. (1725-1805), was a Swiss who practised in London. He was the first to suggest the employment of chloride of arsenic162 in practice. His preparation was admitted into the London Pharmacop?ia.
Erasmus Darwin (1701-1802), a physician of Lichfield, was a true poet of science. His fame rests on the Botanic Garden, in which he describes the Loves of the Plants according to the Linn?an system. His most important scientific work is his Zoonomia, a pathological work, and a treatise79 on generation, in which he anticipated the views of Lamarck. He asks: “Would it be too bold to imagine that in the great length of time since the earth began to exist, perhaps millions of ages before the commencement of the history of mankind, would it be too bold to imagine that all warm-blooded animals have arisen from one living filament163, which the Great First Cause endued with animality, with the power of acquiring new parts, attended with new propensities164, directed by irritations165, sensations, volitions, and associations, and thus possessing the faculty167 of continuing to improve by its own inherent activity, and of delivering down these improvements by generation to its posterity168, world without end!” He believed that plants possess sensation and volition166.
Edward Spry, M.D. (lived in 1756). At the fire of Eddystone lighthouse an old man was injured by the fall of a quantity of molten lead upon him. Dying of his injuries in twelve days, he was examined by Dr. Spry, who stated that he found in the stomach a lump of lead three and three-quarter inches long by one and a half in breadth. As no surgeon would believe this story, Dr. Spry performed a number of experiments upon animals by pouring molten lead down their throats, with the result that at the Royal Society, Dr. Huxham, in his letter to Sir William Watson, “testified to his own belief in Mr. Spry’s veracity169.”1006
John Coakley Lettsom, M.D. (1744-1815), was a learned and amiable170 philanthropist, who published several important medical and scientific works. His Reflections on the Treatment and Cure of Fevers and The Natural History of the Tea Tree appeared in 1772. He wrote the following lines:—
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“When patients sick to me apply,
I physics, bleeds, and sweats ’em.
Sometimes they live, sometimes they die:
What’s that to me? I. Lettsom.”
He gave away immense sums in charity, he was not so unfeeling as his verse would make him appear.
William Stark171 (1742-1770) was the earliest writer who distinguished between tuberculosis172 and scrofula.
Jean Astruc (1684-1766), professor at Montpellier, the oldest of the celebrated French obstetricians, was the author of a work on the diseases of women from the pathological point of view.
Johann E. Wichmann (1740-1802), a scientific physician of Hanover, in 1786 explained the cause of itch173 as due to the itch-mite passing from one individual to another. He experimented upon himself. Bonomo had, however, discovered the insect in the itch pustules in 1687.
Wichmann suggested the contagiousness174 of consumption, whooping175 cough, diarrh?a, and several other complaints.
J. P. Frank (1745-1821) was “the founder of medical police as a distinct department of science.”1007
Hospitals.
The condition of the hospitals for the sick in the eighteenth century was scandalous almost beyond belief. Thus, in the H?tel Dieu of Paris, the mortality at one time was 220 per 1,000; a state of affairs which, however, we surpassed in the present century, when in the British hospitals at Scutari the mortality reached between 400 and 500 per 1,000. In both cases this was due to overcrowding. At the H?tel Dieu two or three small-pox cases, or several surgical176 cases, or sometimes even four lying-in women would be packed into one bed. A large proportion of the beds were purposely made for four patients, and six were frequently crowded in.
John Howard (1726-1790), the philanthropist, by his splendid and devoted labours in connection with the reform of prisons, hospitals, and lazarettos, drew attention to the means of preventing the communication of the plague and other infectious fevers. In the words of Burke430 “his philanthropic spirit led him to dive into the depths of dungeons177; to plunge178 into the infection of hospitals; to survey the mansions179 of sorrow and pain; to take the gauge180 and dimensions of misery181, depression, and contempt; to remember the forgotten; to attend to the neglected; to visit the forsaken182, and to compare and collate183 the distresses184 of all men in all countries.” Not the least of his services were those he rendered to the cause of sanitary185 science and public health.
Théophile de Bordeu (1722-1776) was a professor of anatomy and midwifery at Montpellier. By his great work, Recherches sur le Pouls, he so enraged186 his professional brethren (who, like the Jews, always either maim187 or kill the prophets sent unto them), that he was attacked in his personal character with disgraceful malignity188 for several years. He rendered very great services to the progress of medical science. His physiology was far in advance of his age, and many men have found in his researches on the functions of the glands a mine of wealth for the establishment of their own reputation.
M. F.?X. de Bichat (1771-1802) was a celebrated French anatomist and physiologist3, whose great work, Anatomie Générale, was the foundation of the reform of French medicine at the intellectual awakening189 after the great revolution. Pathology, the science of disease, would have been impossible without such researches as those of Bichat. He first took a “commanding view,” not merely of the organs of the body, but of the tissues of which they are built up. He resolved the complex into its elements, and investigated the structure of each. He completed the overthrow190 of the iatro-mathematical school, regarding the properties of the living tissues as vital actions. He classified the functions as organic and animal, and greatly aided in systematising the phenomena of life.
Mesmerism.
Frederick Anton Mesmer (1733-1815) studied medicine at Vienna. He embraced astrology, and believed in the influence of the stars on living beings. He came to think that cures might be effected by stroking with magnets; afterwards he discarded the magnets, and convinced himself that he could influence others by stroking them with his hands alone. In 1778 Paris was greatly excited over the miraculous191 cures of mesmerism. The medical faculty denounced him as a charlatan192, though a Government Commission in its report admitted many of the facts, while tracing them to physiological causes. The Marquis de Puysegur revolutionised the art of mesmerism by producing all the phenomena without the mummeries and violent means resorted to by Mesmer. Dr. John Elliotson in England in 1830 successfully practised the art.
In 1845 Baron193 von Reichenbach declared he had discovered a new force which he called odyl, and in 1850 his Researches on Magnetism194 were translated into English by Dr. Gregory, professor of chemistry in the University of Edinburgh.
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G. Van Swieten (1700-1772) was a pupil of Boerhaave, and famous in the history of medicine as the founder of the Old Vienna School. He brought about the clinical teaching for which that school has since been so famous. Following the instructions of Paracelsus, he introduced into his practice the use of mercuric perchloride internally in the treatment of syphilis. His commentaries on Boerhaave were considered to be more valuable than the text itself.
De Haen (1704-1776), of the Hague, studied under Boerhaave, and having been recommended by Van Swieten, was invited to Vienna as president of the clinical school in the hospital of that city. Observation, and the simplest treatment in disease, especially in fevers, made up the chief part of his medical system. Purgatives195 and emetics196 and powerful medicines he would use only on the most urgent necessity. Hygiene197, both for the patient and the state, he considered of the highest importance in medical education. Clinical thermometry received great attention from De Haen, who demonstrated that in what is considered by the patient the cold stage of fevers there is really a notable increase in the temperature.
James Yonge (1646-1721), physician and F.R.S., wrote an important treatise on the use of turpentine as a means of arresting h?morrhage, entitled Currus Triumphalis de Terebintho. He described the flap operation in amputations, and was acquainted with the principle of the tourniquet198 for the arrest of bleeding during operations.
John Addenbrooke, M.D., died 1719, leaving by his will four thousand pounds to found a hospital at Cambridge, which now bears his name.
James Drake, M.D. (1667-1707), wrote a work, once deservedly popular, entitled Anthropologia Nova; or, a New System of Anatomy.
John Arbuthnot, M.D. (1658-1735), physician to Queen Anne, was a man of extensive learning and of great scientific abilities, characterized by Thackeray as “one of the wisest, wittiest199, most accomplished, gentlest of mankind.”
Daniel Turner, M.D. (1667-1741), achieved a certain fame as the inventor of an excellent ointment200, still known as “Turner’s Cerate,” composed of oil, wax, and calamine.
Richard Mead, M.D. (1673-1754), was the author of the Mechanical Account of Poisons, a work which at once established his reputation. He was elected a Fellow of the Royal Society in 1703. On the accession of George II. he was appointed physician-in-ordinary to the King. He was the friend of Radcliffe, and like him a generous promoter of science and learning and of unbounded charity to those in misery. It was Mead who persuaded Guy to bequeath his fortune to432 found the noble hospital which bears his name. Mead was a political physician, and it is said by Miss Strickland that his prompt boldness occasioned the peaceable proclamation of George I. Mead’s work on the diseases of the Bible, entitled Medica Sacra, is a curious and interesting treatise. Excellent physician as he was, he recommended pepper and lichen201 as a specific against the bite of a mad dog.
John Freind, M.D. (1675-1728), a learned and accomplished physician, is famous as the author of an elaborate work, The History of Physick from the Time of Galen to the Beginning of the Sixteenth Century. He laid the plan of this important work whilst a prisoner in the Tower, to which he was committed on suspicion of participation202 in the so-called “Bishop203’s plot.” He was liberated204 after about three months’ confinement205 by the firmness of Dr. Mead, who refused to prescribe for Sir Robert Walpole till he consented to admit him to bail206.1008 During his imprisonment207 Freind wrote a Latin letter On certain Kinds of Small Pox.
How near the physicians of Mead’s time came towards the discovery of the germ theory of infectious disorders208 may be seen from his account of the leprosy.1009 In this treatise he says it has been found by experiments that in the plague and other malignant209 eruptive fevers the infection once received into articles of clothing remains210 in them for a long time, and thence passes into human bodies, and “like seeds sown produces the disease peculiar to them.” With reference to the retention211 of the infection by dry walls, he says, “I thought it probable that they may, by a kind of fermentation, produce these hollow, greenish, or reddish strokes,” etc.
Surgeons.
Dominique Anel (1679-1730) was the famous French surgeon who invented the operation for aneurism, which Hunter afterwards modified and called by his own name.
He successfully treated lachrymal fistula, and invented several surgical instruments which are named after him.
J. L. Petit (1674-1750) in 1718 invented the screw tourniquet for compressing bleeding arteries212. He was one of the most famous surgeons in the brightest period of the art in France, and was besides an excellent ophthalmologist.
Le Cat (1700-1768) was the famous lithotomist, and opponent of the doctrines of Haller.
Morand (1697-1773) performed disarticulation of the upper arm.
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Pierre Joseph Desault (1744-1795) was a great French anatomist and surgeon, who instituted a clinical school of surgery at the H?tel Dieu in Paris. He frequently had an audience of six hundred.
He introduced many improvements in surgical practice and in the construction of surgical instruments.
A. Louis (1723-1792) was a distinguished military surgeon.
R. B. Sabatier (1723-1811) was a distinguished surgeon, anatomist, and ophthalmologist, and a man of great and all-round information on medical subjects in general.
P. F. Percy (1754-1825) was a military surgeon who introduced cold-water dressings216 into French surgery.
Antonio Scarpa (1748-1832), the famous Italian anatomist, held the chair of anatomy at Modena, was distinguished in every branch of anatomical research, and investigated the minute anatomy of the nerves and bones. He decided217 the long-debated question whether the heart is supplied with nerves in the affirmative. He wrote on diseases of the eye, on aneurism, and on hernia. He was an elegant scholar, “equally at home in the criticism of the fine arts and in the details of scientific agriculture.”
Amongst the principal Italian surgeons of the century were Bertrandi (1723-1797), Troja (1747-1827), and Palletta (1747-1823).
Of the Germans the great names are, Schmucker (1712-1786), Richter (1742-1812), and Siebold (1736-1807), who first taught surgery clinically in Germany.
Callisen (1740-1824), the great Danish surgeon, and Anel (1741-1801), the founder of the Swedish School of Surgery, are two famous names which must be remembered in the surgical history of the period.
William Cheselden (1688-1752) was famous as a lithotomist and oculist. His dexterity218 in the performance of lithotomy caused marvellous legends to be told of him, it was even said that he had operated in fifty-four seconds. He published his Anatomy of the Human Body in 1713.
Samuel Sharp (1700-1778) excelled in nearly every branch of surgery, and was a skilful operator, who by his efforts to stimulate219 English surgeons to emulate220 the French did much to advance British surgery.
Benjamin Gooch of Norwich, Hey of Leeds, and Park of Liverpool, were also famous in this period.
Percival Pott (1713-1788) was a surgeon to St. Bartholomew’s Hospital, London, whose life formed a sort of epoch221 in the history of434 surgery in England. Samuel Cooper says of him1010 that he was in his time the best practical surgeon, the best lecturer, the best writer on surgery, the best operator of which the metropolis222 could boast.
John Hunter (1728-1793) was a physiologist and surgeon combined, unrivalled in the annals of medicine. He raised surgery, which before his time was little more than a mechanical art, to the rank of a scientific profession. As a pathologist and comparative anatomist, he rendered the greatest services to medicine and surgery. He dissected223 500 different species of animals. One of the most brilliant surgical discoveries of the century was Hunter’s operation for the cure of popliteal aneurism, by tying the femoral artery224 above the tumour225 and without interfering226 with it. He improved the treatment of rupture227 of the tendo achillis, and invented a method of curing lachrymal fistula, and of curing hydrocele radically228 by injection.
He was the first to describe phlebitis (inflammation of the veins229), and he made the discovery that the white blood corpuscles are antecedent to the red. He investigated the subject of inflammation, the results of which he published in his Treatise on the Blood, Inflammation and Gun-shot Wounds. Other works of Hunter’s are his Treatise on the Natural History of the Human Teeth, A Treatise on the Venereal Disease, and Observations on Certain Points of the Animal Economy. “His greatest monument is the splendid museum which he formed by his sole efforts, which he made too when labouring under every disadvantage of deficient230 education and limited means.” His brother-in-law, Sir Everard Home, prepared the catalogue of the museum and then burned Hunter’s manuscripts, probably that he might conceal128 the plagiarisms231 of which he had been guilty in writing his book on Comparative Anatomy. The Government purchased Hunter’s museum from his widow for ￡15,000, upon condition that twenty-four lectures should be delivered every year to members of the college, and that the museum should be open to the public.
Charles White, a Manchester surgeon (circ. 1768), was the first to introduce what is known as conservative surgery. He first resected1011 the humerus, and taught the reduction of shoulder dislocations with the heel in the arm-pit.
The German surgeons in the seventeenth century held simply the position of barbers; they began life by cutting hair, shaving, cupping and bleeding, and then rose to be dressers of wounds and ulcers232, and to treat fractures and dislocations.1012 In 1713, Berlin acquired its first435 anatomical theatre for the instruction of military doctors and “medico-surgeons.” Dresden and Hanover began to improve the education of clever barbers about the middle of the eighteenth century. The Military Medical School of Vienna was opened in 1781. Barbers and bathmen in the eighteenth century were trained into district medical officers and surgeons by a course of instruction lasting233 from two to three years. In Holland students were privileged to assist in operations at the hospitals. The first surgical clinic in Germany was established at Würzburg, in 1769. The Vienna surgical clinic arose in 1774. The greatest teacher of surgery in Germany, A.?G. Richter, gave clinical instruction at G?ttingen, in 1781.1013
G. M. Thilenius in 1784 performed the first division of the tendo achillis for the cure of club-foot.
Justus Arneman (1763-1807) was a surgical professor at G?ttingen, who wrote a system of surgery and advanced the study of diseases of the ear.
Camper (1722-1789), a Dutch surgeon of a mechanical turn of mind, made improvements in trusses. Leguin, a Frenchman, was the first to employ steel springs in trusses (1663). Tipharie in 1761 introduced the double truss.1014
Obstetricians.
Johann Palfyn (1649-1730), a celebrated obstetric physician, in 1721 invented, or rather re-introduced, a species of forceps in difficult labour.
Hugh Chamberlen, M.D. (1664-1728), was the most famous man-midwife of his day. His name is for ever associated with the invention of the obstetric forceps—a noble instrument, which has saved more lives than any mechanical invention ever associated with the healing art. A monument was erected to his memory in Westminster Abbey, with a long Latin epitaph by Bishop Atterbury.
William Smellie (1680-1763), a distinguished English obstetric physician, improved the midwifery forceps and suggested and performed various operations in obstetric practice.
William Bromfield (1712-1792) founded the Lock Hospital, London. He invented a tenaculum (a fine sharp hook by which the mouths of bleeding arteries are drawn out). He was a celebrated operator, and wrote a work on surgery.
The Medical College of Philadelphia was the first institution estab436lished in North America to give medical instruction. It was organized in May, 1765, by Drs. Shippen and Morgan. The University of Pennsylvania developed its medical department from this humble234 beginning.
Alexander Monro (1697-1767) was a very eminent surgeon and anatomist of Edinburgh, whose Medical School owes more to him probably than to any other individual. He wrote on the Anatomy of the Bones, and an Essay on Comparative Anatomy.
Frank Nicholls, M.D. (1699-1778), was a famous anatomist and physiologist at Oxford. “He was the inventor of corroded236 anatomical preparations, and one of the first to study and teach the minute anatomy of tissues, in other words, general, as distinguished from regional and descriptive anatomy.”1015 He was one of the first to describe correctly the mode of the production of aneurism, and he distinctly recognised the existence and function of the vaso-motor nerves.1016
Browne Langrish, M.D., was elected a Fellow of the Royal Society in 1734. He was the author of several medical treatises, one of which was entitled Physical Experiments upon Brutes237 to discover a Method of dissolving Stone in the Bladder by Injections; to which is added a course of Experiments with the Lauro-Cerasus; on Fumes238 of Sulphur, etc. 8vo. Lond., 1746. His researches on the action of cherry laurel water are said to have suggested the use of prussic acid in medicine.1017
John Fothergill, M.D. (1712-1780), was a distinguished botanist, who collected a great number of rare plants from all parts of the world.
William Cruikshank (1745-1800) was an anatomist who discovered urea.
Stephen Hales (1677-1761), an experimental physiologist and pathologist, produced dropsy by injecting water into the veins of animals, and investigated by experiments on animals the relative movements of the blood.
Antonio Valsalva (1666-1723), a great Italian anatomist, held the professor’s chair at Bologna and wrote a valuable treatise upon the ear and its anatomy.
Giovanni Santorini (1681-1737) was a Venetian anatomist whose investigations in the anatomy of the larynx, nose, face, etc., have immortalised his name in connection with several structures of those parts.
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Giovanni B. Morgagni (1682-1772) was the great founder of pathological anatomy. He was a pupil of Valsalva. His famous book on pathological anatomy was not published until he was in his 79th year. He was the author of the maxim130 that “observations should be weighed, not counted.” The researches in morbid anatomy carried out by Morgagni formed an epoch in the history of modern medicine, which may indeed be said to rest on the two methods of Sydenham and Morgagni. The work of the Italian anatomist was complementary to that of the English Hippocrates, who neglected anatomy. Morgagni and the “Encyclop?dic Haller,” whom we are next to consider, were two of the brightest medical lights of the century.
Albert von Haller (1708-1777), surnamed “the Great,” was a Swiss physician of Berne, who was not only a distinguished scientist, but a man of letters and a famous poet. He studied comparative anatomy at Tübingen; in 1725 he removed to Leyden, which at that time was the first medical school in Europe. He visited England in 1727, and made the acquaintance of Sir Hans Sloane, Cheselden, Dr. James Douglas, and other eminent persons. Leaving London, he went to Paris, but having been detected by the police in dissecting239 in his lodgings240, he had to leave France, and he went to Basle to continue his investigations in anatomy; there he studied mathematics under John Bernoulli, and, having imbibed241 a taste for botany, studied the flora242 of Switzerland, on which he afterwards published a work. In 1729 he returned to Berne and lectured on anatomy; invited in 1726 to accept the professorship of anatomy, surgery, and botany in the newly founded University of G?ttingen, he removed to that city, and by his influence a botanical garden, an anatomical theatre, a school of surgery and midwifery were established there. In 1747 he published his most valuable work, the Prim243? Line? Physiologi? which was used as a text-book in medical schools.
Van Swieten (1700-1772), the pupil of Boerhaave, established the first clinical institution in Germany. He was with Sanchez the first to use corrosive244 sublimate245 in medicine. To his exertions246 it was due that the teaching of medicine was greatly improved in Austria.
J. F. Meckel (1724-1774) was an anatomist whose researches on the nerves, blood-vessels, glands, etc., have greatly contributed to our knowledge of their physiological functions.
J. C. Peyer (1653-1712) and J. C. Bruner (1653-1727) discovered the glands in the intestines247 which are known to this day by their names.
A. Pacchioni (1665-1726) described the glands we call in his honour “Pacchionian.” W. Cowper (1666-1709) discovered those which bear his name. M. Naboth (1675-1721) described the struc438tures we call ovula Nabothi. H. Meibom (1638-1700) discovered the glands of the eyelids248 named after him.
Walter Charlton, M.D. (1619-1707), anatomist, a voluminous writer, was to some extent a follower25 of Van Helmont.
Thomas Fuller, M.D. (died 1734), published several pharmacop?ias and an account of eruptive fevers, with several other works.
Nehemiah Grew, M.D. (born about 1641), wrote The Anatomy of Plants, with an Idea of a Philosophical History of Plants, which Sprengel calls opus absolutum et immortale. Hallam says,1018 “no man, perhaps, who created a science has carried it further than Grew; few discoveries of great importance have been made in the mere anatomy of plants since his time.” His great discovery was the sexual system of plants; “that the sexual system is universal in the vegetable kingdom, and that the dust of the anther? is endowed with an impregnating power.”1019
He was the first to obtain sulphate of magnesia from the Epsom waters, and to investigate its properties. His treatise on Epsom salts was published in 1697.
William Briggs, M.D. (died 1704), was famous for his “skill in difficult cases of the eye.”
Edward Tyson, M.D. (died 1708), wrote on anatomy; he was the Carus of Garth’s Dispensary, and the discoverer of “Tyson’s Glands.”
William Pitcairn, M.D. (1711-1791), was an accomplished botanist. He lived in the Upper Street, Islington, where he had a botanical garden five acres in extent, stocked with the scarcest and most valuable plants. He introduced into St. Bartholomew’s Hospital a much freer use of opium in the treatment of disease, and especially of fevers, than had hitherto been customary, and that with the greatest benefit to the patients.
Peter Shaw, M.D. (1694-1763), greatly facilitated the study of chemistry in England by his translations of the chemical works of Stahl and Boerhaave, as well as by his own works. He edited the works of Bacon and Boyle, and published a number of books on medicine and chemistry.
William Hunter, M.D. (1718-1783), was an earnest and devoted anatomist and obstetrician. He was a pupil of Cullen, and was so successful a practitioner249 that he expended250 ￡100,000 upon his house and anatomical collection, etc. The Hunterian Museum of the University of Glasgow was formed from this collection. The famous John Hunter was his younger brother.
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Thomas Dimsdale, M.D. (1711-1800), a celebrated promoter of inoculation for small-pox, acquired a great reputation and immense wealth by the process. Catherine II. of Russia paid him enormous sums for successful inoculations, and gave him a barony.
William Heberden, M.D. (1710-1801), lectured on Materia Medica at Cambridge. Dr. Munk1020 gives an interesting extract from one of Heberden’s lectures on Mithridatum and Theriaca, the famous classic medicines; he proves that the only poisons known to the ancients were hemlock251, monk’s-hood, and those of venomous beasts, and that they had no antidotes252 for these. He says that the first accounts of powerful poisons concealed in seals or rings, poisonous vapours in gloves and letters, etc., are idle inventions of ignorant and superstitious253 persons.
Buffon (1707-1788) was the celebrated French naturalist254 to whom “we owe our first clear and practical connection of the distribution of animals with the geography of the globe.”
George Armstrong in 1769 opened the first children’s hospital in Europe; he was the physician who first devoted special attention to the diseases of children. Armstrong was a London man, and died 1781.
Joh. E. Gredring (1718-1775) was a German physician who was the first to investigate “the seat, cause, and diagnosis255 of insanity256.”1021
James Currie (1756-1805) advocated the cold-water treatment of typhus fever patients, and thus introduced a method of treatment which in one form or another is used at the present time for reducing the temperature of the body in such cases. Currie determined257 the temperature by the thermometer.
Lady Wortley Montagu (1690-1762) is famous in the annals of medicine for her courageous258 adoption259 of the Turkish practice of inoculation for small-pox in the case of her own son. By her zealous260 advocacy she was instrumental in causing the practice to be introduced into England in 1721. Dr. Keith having subjected his son to the operation, experiments were conducted upon criminals by Maitland, and these having been successful, the Prince of Wales and the royal princesses were inoculated261 by Mead. On behalf of the Almighty262, whose province was supposed to be trespassed263 upon by these and similar proceedings264, the practice was violently opposed by the clergy265 and others.
Edward Jenner (1749-1823) introduced the practice of vaccination as a preventive of small-pox. He commenced his investigations concerning cow-pox about the year 1776. The practice of inoculation440 with the virus of small-pox, which had been introduced into England through the suggestion of Lady Wortley Montagu, indirectly led Jenner to his grand discovery. His attention was excited by finding that certain persons to whom he attempted to communicate small-pox by inoculation were not susceptible266 to the disease; on pursuing his inquiries267 he found that these persons had undergone cow-pox—a complaint common among the dairy-servants and farmers in Gloucestershire, and that these people were aware that cow-pox in some way was a preventive against the small-pox. Local medical men had long been acquainted with this idea, but had paid no attention to it, considering it merely a popular and groundless belief. Jenner’s genius, however, led him to divine the truth of the matter and turn it to practical advantage. The disease which affects the udder of the cow was found to be inoculable268 in the human subject, and could be propagated from one person to another, rendering269 those who had passed through the complaint secure from an attack of small-pox. Having confided270 the fact of this discovery to some medical friends, it was taken up in 1796 by Mr. Clive, of St. Thomas’s Hospital, who introduced vaccination into London. Vaccination was adopted in the army and navy, and Jenner was honoured by professional distinctions and a parliamentary grant of ￡20,000. He was made a Fellow of the Royal Society, and his fame and the benefits of his discovery were rapidly extended to continental nations.
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1
anatomy
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| n.解剖学，解剖；功能，结构，组织 | |
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physiologists
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| n.生理学者( physiologist的名词复数 )；生理学( physiology的名词复数 )；生理机能 | |
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physiologist
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| n.生理学家 | |
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inoculation
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| n.接芽；预防接种 | |
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vaccination
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| n.接种疫苗，种痘 | |
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indefatigable
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| adj.不知疲倦的，不屈不挠的 | |
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devoted
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| adj.忠诚的，忠实的，热心的，献身于...的 | |
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philosophical
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| adj.哲学家的，哲学上的，达观的 | |
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strictly
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| adv.严厉地，严格地；严密地 | |
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benefactors
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| n.捐助者，施主( benefactor的名词复数 )；恩人 | |
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distinguished
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| adj.卓越的，杰出的，著名的 | |
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affiliated
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| adj. 附属的, 有关连的 | |
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martyrs
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| n.martyr的复数形式；烈士( martyr的名词复数 )；殉道者；殉教者；乞怜者（向人诉苦以博取同情） | |
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partially
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| adv.部分地，从某些方面讲 | |
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speculation
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| n.思索，沉思；猜测；投机 | |
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sect
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| n.派别，宗教，学派，派系 | |
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sects
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| n.宗派，教派( sect的名词复数 ) | |
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indirectly
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| adv.间接地，不直接了当地 | |
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psychical
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| adj.有关特异功能现象的；有关特异功能官能的；灵魂的；心灵的 | |
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derived
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| vi.起源；由来；衍生；导出v.得到( derive的过去式和过去分词 )；（从…中）得到获得；源于；（从…中）提取 | |
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doctrine
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| n.教义；主义；学说 | |
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imbued
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| v.使（某人/某事）充满或激起（感情等）( imbue的过去式和过去分词 )；使充满；灌输；激发（强烈感情或品质等） | |
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doctrines
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| n.教条( doctrine的名词复数 )；教义；学说；（政府政策的）正式声明 | |
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interpretations
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| n.解释( interpretation的名词复数 )；表演；演绎；理解 | |
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follower
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| n.跟随者；随员；门徒；信徒 | |
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followers
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| 追随者( follower的名词复数 )； 用户； 契据的附面； 从动件 | |
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absurdities
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| n.极端无理性( absurdity的名词复数 )；荒谬；谬论；荒谬的行为 | |
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pharmaceutical
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| adj.药学的，药物的；药用的，药剂师的 | |
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ferment
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| vt.使发酵；n./vt.（使）激动，（使）动乱 | |
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opposition
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| n.反对，敌对 | |
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digestion
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| n.消化，吸收 | |
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saliva
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| n.唾液，口水 | |
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gall
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| v.使烦恼，使焦躁，难堪；n.磨难 | |
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physiology
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| n.生理学，生理机能 | |
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pharmacy
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| n.药房，药剂学，制药业，配药业，一批备用药品 | |
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gland
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| n.腺体，(机)密封压盖，填料盖 | |
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eminent
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| adj.显赫的，杰出的，有名的，优良的 | |
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reign
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| n.统治时期，统治，支配，盛行；v.占优势 | |
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brewer
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| n. 啤酒制造者 | |
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superseded
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| [医]被代替的，废弃的 | |
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mere
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| adj.纯粹的；仅仅，只不过 | |
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phenomena
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| n.现象 | |
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elucidate
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| v.阐明，说明 | |
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undoubtedly
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| adv.确实地，无疑地 | |
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purely
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| adv.纯粹地，完全地 | |
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hydraulic
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| adj.水力的；水压的，液压的；水力学的 | |
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investigator
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| n.研究者，调查者，审查者 | |
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velocity
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| n.速度，速率 | |
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49
sieves
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| 筛，漏勺( sieve的名词复数 ) | |
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50
cylindrical
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| adj.圆筒形的 | |
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51
triangular
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| adj.三角（形）的，三者间的 | |
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52
vessels
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| n.血管( vessel的名词复数 )；船；容器；（具有特殊品质或接受特殊品质的）人 | |
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53
investigation
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| n.调查，调查研究 | |
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54
glandular
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| adj.腺体的 | |
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55
mead
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| n.蜂蜜酒 | |
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56
adherents
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| n.支持者，拥护者( adherent的名词复数 )；党羽；徒子徒孙 | |
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57
mathematician
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| n.数学家 | |
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58
mathematicians
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| 数学家( mathematician的名词复数 ) | |
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59
endued
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| v.授予，赋予（特性、才能等）( endue的过去式和过去分词 ) | |
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60
diffused
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| 散布的，普及的，扩散的 | |
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61
speculations
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|
| n.投机买卖( speculation的名词复数 )；思考；投机活动；推断 | |
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62
modification
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| n.修改，改进，缓和，减轻 | |
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63
pervading
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| v.遍及，弥漫( pervade的现在分词 ) | |
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64
secretions
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| n.分泌（物）( secretion的名词复数 ) | |
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65
secretion
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| n.分泌 | |
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66
glands
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| n.腺( gland的名词复数 ) | |
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67
secretes
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|
| v.（尤指动物或植物器官）分泌( secrete的第三人称单数 )；隐匿，隐藏 | |
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68
peculiar
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|
| adj.古怪的，异常的；特殊的，特有的 | |
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69
physiological
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|
| adj.生理学的，生理学上的 | |
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70
irritability
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|
| n.易怒 | |
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71
varied
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|
| adj.多样的，多变化的 | |
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72
conversant
|
|
| adj.亲近的，有交情的，熟悉的 | |
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73
fully
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|
| adv.完全地，全部地，彻底地；充分地 | |
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74
botanist
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|
| n.植物学家 | |
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75
encumbered
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|
| v.妨碍，阻碍，拖累( encumber的过去式和过去分词 ) | |
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76
ascertain
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|
| vt.发现，确定，查明，弄清 | |
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77
aphorisms
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| 格言，警句( aphorism的名词复数 ) | |
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78
treatises
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|
| n.专题著作，专题论文，专著( treatise的名词复数 ) | |
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79
treatise
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|
| n.专著；(专题)论文 | |
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80
systematic
|
|
| adj.有系统的，有计划的，有方法的 | |
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81
previously
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|
| adv.以前，先前（地） | |
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82
remarkable
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|
| adj.显著的，异常的，非凡的，值得注意的 | |
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83
perspicuity
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|
| n.（文体的）明晰 | |
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84
elegance
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|
| n.优雅；优美，雅致；精致，巧妙 | |
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85
condensation
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|
| n.压缩，浓缩；凝结的水珠 | |
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86
Mandarin
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|
| n.中国官话，国语，满清官吏；adj.华丽辞藻的 | |
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87
extremity
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|
| n.末端，尽头；尽力；终极；极度 | |
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88
sentient
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|
| adj.有知觉的，知悉的；adv.有感觉能力地 | |
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89
sensory
|
|
| adj.知觉的，感觉的，知觉器官的 | |
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90
faculties
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|
| n.能力( faculty的名词复数 )；全体教职员；技巧；院 | |
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91
harmonious
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|
| adj.和睦的，调和的，和谐的，协调的 | |
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92
exclusion
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|
| n.拒绝，排除，排斥，远足，远途旅行 | |
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93
lamented
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|
| adj.被哀悼的，令人遗憾的v.（为…）哀悼，痛哭，悲伤( lament的过去式和过去分词 ) | |
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94
skilful
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|
| (=skillful)adj.灵巧的，熟练的 | |
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95
versed
|
|
| adj. 精通，熟练 | |
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96
applied
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|
| adj.应用的；v.应用，适用 | |
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97
affinity
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|
| n.亲和力，密切关系 | |
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98
mutual
|
|
| adj.相互的，彼此的；共同的，共有的 | |
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99
virtue
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|
| n.德行，美德；贞操；优点；功效，效力 | |
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100
antipathy
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|
| n.憎恶；反感，引起反感的人或事物 | |
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101
tracts
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|
| 大片土地( tract的名词复数 )； 地带； （体内的）道； （尤指宣扬宗教、伦理或政治的）短文 | |
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102
materialism
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|
| n.［哲］唯物主义，唯物论；物质至上 | |
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103
morbid
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|
| adj.病的；致病的；病态的；可怕的 | |
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104
combustible
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|
| a. 易燃的,可燃的; n. 易燃物,可燃物 | |
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105
noxious
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|
| adj.有害的，有毒的；使道德败坏的，讨厌的 | |
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106
counteract
|
|
| vt.对…起反作用，对抗，抵消 | |
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107
Vogue
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|
| n.时髦，时尚；adj.流行的 | |
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108
inert
|
|
| adj.无活动能力的，惰性的；迟钝的 | |
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109
placebos
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|
| n.（给无实际治疗需要者的）安慰剂( placebo的名词复数 )；安慰物；宽心话；（试验药物用的）无效对照剂 | |
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110
invaluable
|
|
| adj.无价的，非常宝贵的，极为贵重的 | |
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111
opium
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|
| n.鸦片；adj.鸦片的 | |
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112
atoned
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|
| v.补偿，赎（罪）( atone的过去式和过去分词 )；补偿，弥补，赎回 | |
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113
vomiting
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| 吐 | |
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114
physicist
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|
| n.物理学家，研究物理学的人 | |
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115
disciple
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|
| n.信徒，门徒，追随者 | |
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116
scripture
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|
| n.经文，圣书，手稿；Scripture:(常用复数)《圣经》，《圣经》中的一段 | |
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117
whatsoever
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|
| adv.（用于否定句中以加强语气）任何；pron.无论什么 | |
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118
secretory
|
|
| adj.分泌的，能分泌的，促分泌的n.分泌腺，分泌器官 | |
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119
dilating
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|
| v.（使某物）扩大，膨胀，张大( dilate的现在分词 ) | |
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120
vascular
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|
| adj.血管的，脉管的 | |
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121
virtues
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|
| 美德( virtue的名词复数 )； 德行； 优点； 长处 | |
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122
nostrum
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|
| n.秘方；妙策 | |
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123
anodyne
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|
| n.解除痛苦的东西，止痛剂 | |
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124
dissection
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|
| n.分析；解剖 | |
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125
paupers
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|
| n.穷人( pauper的名词复数 )；贫民；贫穷 | |
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126
adherence
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|
| n.信奉，依附，坚持，固着 | |
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127
superfluous
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|
| adj.过多的，过剩的，多余的 | |
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128
conceal
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|
| v.隐藏，隐瞒，隐蔽 | |
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129
concealed
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| a.隐藏的，隐蔽的 | |
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130
maxim
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|
| n.格言，箴言 | |
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131
maxims
|
|
| n.格言，座右铭( maxim的名词复数 ) | |
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132
fatigue
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|
| n.疲劳，劳累 | |
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133
dissertations
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|
| 专题论文，学位论文( dissertation的名词复数 ) | |
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134
accomplished
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|
| adj.有才艺的；有造诣的；达到了的 | |
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135
discreet
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|
| adj.(言行)谨慎的；慎重的；有判断力的 | |
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136
utterances
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|
| n.发声( utterance的名词复数 )；说话方式；语调；言论 | |
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137
advancement
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|
| n.前进，促进，提升 | |
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138
observatory
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|
| n.天文台，气象台，瞭望台，观测台 | |
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139
Oxford
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|
| n.牛津（英国城市） | |
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140
rheumatism
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|
| n.风湿病 | |
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141
diabetes
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|
| n.糖尿病 | |
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142
investigations
|
|
| （正式的）调查( investigation的名词复数 )； 侦查； 科学研究； 学术研究 | |
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143
specimen
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|
| n.样本，标本 | |
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144
induction
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|
| n.感应，感应现象 | |
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145
simplicity
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|
| n.简单，简易；朴素；直率，单纯 | |
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146
formerly
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|
| adv.从前，以前 | |
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147
ornaments
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|
| n.装饰( ornament的名词复数 )；点缀；装饰品；首饰v.装饰，点缀，美化( ornament的第三人称单数 ) | |
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148
banished
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|
| v.放逐，驱逐( banish的过去式和过去分词 ) | |
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149
scurvy
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|
| adj.下流的，卑鄙的，无礼的；n.坏血病 | |
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150
drawn
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|
| v.拖，拉，拔出；adj.憔悴的，紧张的 | |
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151
qualified
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|
| adj.合格的，有资格的，胜任的，有限制的 | |
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152
benign
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|
| adj.善良的，慈祥的；良性的，无危险的 | |
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153
ardent
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|
| adj.热情的，热烈的，强烈的，烈性的 | |
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154
Founder
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|
| n.创始者，缔造者 | |
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155
eruption
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|
| n.火山爆发；（战争等）爆发；（疾病等）发作 | |
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156
ERECTED
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|
| adj. 直立的，竖立的，笔直的 vt. 使 ... 直立，建立 | |
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157
continental
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|
| adj.大陆的，大陆性的，欧洲大陆的 | |
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158
stimulants
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|
| n.兴奋剂( stimulant的名词复数 )；含兴奋剂的饮料；刺激物；激励物 | |
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159
stimulus
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|
| n.刺激，刺激物，促进因素，引起兴奋的事物 | |
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160
purging
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|
| 清洗； 清除； 净化； 洗炉 | |
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161
celebrated
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|
| adj.有名的，声誉卓著的 | |
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162
arsenic
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|
| n.砒霜，砷；adj.砷的 | |
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163
filament
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|
| n.细丝；长丝；灯丝 | |
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164
propensities
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|
| n.倾向，习性( propensity的名词复数 ) | |
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165
irritations
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|
| n.激怒( irritation的名词复数 )；恼怒；生气；令人恼火的事 | |
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166
volition
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|
| n.意志；决意 | |
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167
faculty
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|
| n.才能；学院，系；(学院或系的)全体教学人员 | |
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168
posterity
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|
| n.后裔，子孙，后代 | |
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169
veracity
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|
| n.诚实 | |
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170
amiable
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|
| adj.和蔼可亲的，友善的，亲切的 | |
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171
stark
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|
| adj.荒凉的；严酷的；完全的；adv.完全地 | |
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172
tuberculosis
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|
| n.结核病，肺结核 | |
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173
itch
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|
| n.痒，渴望，疥癣；vi.发痒，渴望 | |
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174
contagiousness
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|
| [医] （接）触（传）染性 | |
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175
whooping
|
|
| 发嗬嗬声的，发咳声的 | |
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176
surgical
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|
| adj.外科的，外科医生的，手术上的 | |
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177
dungeons
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|
| n.地牢( dungeon的名词复数 ) | |
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178
plunge
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|
| v.跳入，(使)投入，(使)陷入；猛冲 | |
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179
mansions
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|
| n.宅第，公馆，大厦( mansion的名词复数 ) | |
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180
gauge
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|
| v.精确计量；估计；n.标准度量；计量器 | |
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181
misery
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| n.痛苦，苦恼，苦难；悲惨的境遇，贫苦 | |
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182
Forsaken
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| adj. 被遗忘的, 被抛弃的 动词forsake的过去分词 | |
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183
collate
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| vt.(仔细)核对，对照；(书籍装订前)整理 | |
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184
distresses
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| n.悲痛( distress的名词复数 )；痛苦；贫困；危险 | |
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185
sanitary
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| adj.卫生方面的，卫生的，清洁的，卫生的 | |
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186
enraged
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| 使暴怒( enrage的过去式和过去分词 )； 歜； 激愤 | |
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187
maim
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| v.使残废，使不能工作，使伤残 | |
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188
malignity
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| n.极度的恶意，恶毒；（病的）恶性 | |
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189
awakening
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| n.觉醒，醒悟 adj.觉醒中的；唤醒的 | |
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190
overthrow
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| v.推翻，打倒，颠覆；n.推翻，瓦解，颠覆 | |
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191
miraculous
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| adj.像奇迹一样的，不可思议的 | |
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192
charlatan
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| n.骗子；江湖医生；假内行 | |
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193
baron
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| n.男爵；(商业界等)巨头，大王 | |
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194
magnetism
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| n.磁性，吸引力，磁学 | |
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195
purgatives
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| 泻剂( purgative的名词复数 ) | |
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196
emetics
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| n.催吐药( emetic的名词复数 ) | |
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197
hygiene
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| n.健康法，卫生学 （a.hygienic） | |
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198
tourniquet
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| n.止血器，绞压器，驱血带 | |
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199
wittiest
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| 机智的，言辞巧妙的，情趣横生的( witty的最高级 ) | |
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200
ointment
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| n.药膏，油膏，软膏 | |
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201
lichen
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| n.地衣, 青苔 | |
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202
participation
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| n.参与，参加，分享 | |
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203
bishop
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| n.主教，（国际象棋）象 | |
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204
liberated
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| a.无拘束的，放纵的 | |
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205
confinement
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| n.幽禁，拘留，监禁；分娩；限制，局限 | |
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206
bail
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| v.舀（水），保释；n.保证金，保释，保释人 | |
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207
imprisonment
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| n.关押，监禁，坐牢 | |
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208
disorders
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| n.混乱( disorder的名词复数 )；凌乱；骚乱；（身心、机能）失调 | |
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209
malignant
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| adj.恶性的，致命的；恶意的，恶毒的 | |
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210
remains
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| n.剩余物，残留物；遗体，遗迹 | |
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211
retention
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| n.保留，保持，保持力，记忆力 | |
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212
arteries
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| n.动脉( artery的名词复数 )；干线，要道 | |
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213
thigh
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| n.大腿；股骨 | |
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214
oculist
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| n.眼科医生 | |
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215
joint
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| adj.联合的，共同的；n.关节，接合处；v.连接，贴合 | |
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216
dressings
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| n.敷料剂；穿衣( dressing的名词复数 )；穿戴；（拌制色拉的）调料；（保护伤口的）敷料 | |
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217
decided
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| adj.决定了的，坚决的；明显的，明确的 | |
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218
dexterity
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| n.(手的)灵巧，灵活 | |
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219
stimulate
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| vt.刺激，使兴奋；激励，使…振奋 | |
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220
emulate
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| v.努力赶上或超越，与…竞争；效仿 | |
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221
epoch
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| n.(新)时代；历元 | |
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222
metropolis
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| n.首府；大城市 | |
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223
dissected
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| adj.切开的，分割的，（叶子）多裂的v.解剖（动物等）( dissect的过去式和过去分词 )；仔细分析或研究 | |
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224
artery
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| n.干线，要道；动脉 | |
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225
tumour
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| n.(tumor)(肿)瘤，肿块 | |
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226
interfering
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| adj. 妨碍的 动词interfere的现在分词 | |
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227
rupture
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| n.破裂；(关系的)决裂；v.(使)破裂 | |
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228
radically
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| ad.根本地，本质地 | |
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229
veins
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| n.纹理；矿脉( vein的名词复数 )；静脉；叶脉；纹理 | |
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230
deficient
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| adj.不足的，不充份的，有缺陷的 | |
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231
plagiarisms
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| n.剽窃( plagiarism的名词复数 )；抄袭；剽窃物；抄袭物 | |
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232
ulcers
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| n.溃疡( ulcer的名词复数 )；腐烂物；道德败坏；腐败 | |
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233
lasting
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| adj.永久的，永恒的；vbl.持续，维持 | |
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234
humble
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| adj.谦卑的，恭顺的；地位低下的；v.降低，贬低 | |
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235
botanists
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| n.植物学家，研究植物的人( botanist的名词复数 ) | |
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236
corroded
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| 已被腐蚀的 | |
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237
brutes
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| 兽( brute的名词复数 )； 畜生； 残酷无情的人； 兽性 | |
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238
fumes
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| n.(强烈而刺激的)气味，气体 | |
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239
dissecting
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| v.解剖（动物等）( dissect的现在分词 )；仔细分析或研究 | |
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240
lodgings
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| n. 出租的房舍, 寄宿舍 | |
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241
imbibed
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| v.吸收( imbibe的过去式和过去分词 )；喝；吸取；吸气 | |
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242
flora
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| n.(某一地区的)植物群 | |
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243
prim
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| adj.拘泥形式的，一本正经的；n.循规蹈矩，整洁；adv.循规蹈矩地，整洁地 | |
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244
corrosive
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| adj.腐蚀性的；有害的；恶毒的 | |
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245
sublimate
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| v.(使)升华，净化 | |
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246
exertions
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| n.努力( exertion的名词复数 )；费力；（能力、权力等的）运用；行使 | |
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247
intestines
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| n.肠( intestine的名词复数 ) | |
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248
eyelids
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| n.眼睑( eyelid的名词复数 )；眼睛也不眨一下；不露声色；面不改色 | |
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249
practitioner
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| n.实践者，从事者；(医生或律师等)开业者 | |
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250
expended
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| v.花费( expend的过去式和过去分词 )；使用（钱等）做某事；用光；耗尽 | |
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251
hemlock
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| n.毒胡萝卜，铁杉 | |
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252
antidotes
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| 解药( antidote的名词复数 )； 解毒剂； 对抗手段； 除害物 | |
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253
superstitious
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| adj.迷信的 | |
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254
naturalist
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| n.博物学家(尤指直接观察动植物者) | |
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255
diagnosis
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| n.诊断，诊断结果，调查分析，判断 | |
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256
insanity
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| n.疯狂，精神错乱；极端的愚蠢，荒唐 | |
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257
determined
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| adj.坚定的；有决心的 | |
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258
courageous
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| adj.勇敢的，有胆量的 | |
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259
adoption
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| n.采用，采纳，通过；收养 | |
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260
zealous
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| adj.狂热的，热心的 | |
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261
inoculated
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| v.给…做预防注射( inoculate的过去式和过去分词 ) | |
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262
almighty
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| adj.全能的，万能的；很大的，很强的 | |
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263
trespassed
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| （trespass的过去式与过去分词形式） | |
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264
proceedings
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| n.进程，过程，议程；诉讼(程序)；公报 | |
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265
clergy
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| n.[总称]牧师，神职人员 | |
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266
susceptible
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| adj.过敏的，敏感的；易动感情的，易受感动的 | |
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267
inquiries
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| n.调查( inquiry的名词复数 )；疑问；探究；打听 | |
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268
inoculable
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| adj.可接种的，可用作接种的 | |
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269
rendering
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| n.表现，描写 | |
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270
confided
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| v.吐露（秘密，心事等）( confide的过去式和过去分词 )；（向某人）吐露（隐私、秘密等） | |
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